Center for iPS Cell Research and Application (CiRA)

Questionable practices identified by an examination of therapeutic plan reviews performed by certified committees under the Act on the Safety of Regenerative Medicine

Questionable practices identified by an examination of therapeutic plan reviews performed by certified committees under the Act on the Safety of Regenerative Medicine

Pathogenesis of skeletal muscle lesions in spinal muscular atrophy

Cyclic RNA Switches that Regulate Gene Expression in a Cell Type-Specific Manner

Development of a versatile method to synthesize functional mRNAs with diverse 5' cap structures

Development of a versatile method to synthesize functional mRNAs with diverse 5' cap structures

T-Cell Responses in the Elderly Rise Slowly and Contract Quickly ~Learning About Individual and Age Differences in Immune Response From COVID-19 Vaccinations~

Modeling amyotrophic lateral sclerosis (ALS) in pigs -Developing a new experimental platform to test ALS gene and cell therapies-

Modeling amyotrophic lateral sclerosis (ALS) in pigs -Developing a new experimental platform to test ALS gene and cell therapies-

Reproducing skeletal muscle pathology of myotonic dystrophy using patient-derived iPS cells and establishing a new system to quantitatively evaluate drug efficacy

Reproducing skeletal muscle pathology of myotonic dystrophy using patient-derived iPS cells and establishing a new system to quantitatively evaluate drug efficacy

Genetic modifications boosting CAR signaling improve the therapeutic efficacy of iPSC-derived CAR-T cells against solid tumors

Phase I clinical trial of bosutinib for amyotrophic lateral sclerosis (ALS); iDReAM study

A new sensitive method to detect for minute amounts of contaminating undifferentiated iPS cells

A new sensitive method to detect for minute amounts of contaminating undifferentiated iPS cells

2022 Clarivate Highly Cited Researchers include six from KyotoU

Immunosuppressive regimens after a heart transplant can hamper good therapeutic progressions in fibrosis

A novel method for generating naive human iPS cells with significantly higher differentiation potency

A novel method for generating naive human iPS cells with significantly higher differentiation potency

Successful generation of human iPS cell-derived mesenchymal cells capable of producing alveolar organoids

Successful generation of human iPS cell-derived mesenchymal cells capable of producing alveolar organoids

An important host factor in SARS-CoV-2 infection, identified using iPS cell and organoid technology

An important host factor in SARS-CoV-2 infection, identified using iPS cell and organoid technology

Human ‘blastoids’ offer medical hope but also deep ethical challenges

Human ‘blastoids’ offer medical hope but also deep ethical challenges