Center for iPS Cell Research and Application (CiRA)

T-Cell Responses in the Elderly Rise Slowly and Contract Quickly ~Learning About Individual and Age Differences in Immune Response From COVID-19 Vaccinations~

Modeling amyotrophic lateral sclerosis (ALS) in pigs -Developing a new experimental platform to test ALS gene and cell therapies-

Modeling amyotrophic lateral sclerosis (ALS) in pigs -Developing a new experimental platform to test ALS gene and cell therapies-

Reproducing skeletal muscle pathology of myotonic dystrophy using patient-derived iPS cells and establishing a new system to quantitatively evaluate drug efficacy

Reproducing skeletal muscle pathology of myotonic dystrophy using patient-derived iPS cells and establishing a new system to quantitatively evaluate drug efficacy

Genetic modifications boosting CAR signaling improve the therapeutic efficacy of iPSC-derived CAR-T cells against solid tumors

Phase I clinical trial of bosutinib for amyotrophic lateral sclerosis (ALS); iDReAM study

A new sensitive method to detect for minute amounts of contaminating undifferentiated iPS cells

A new sensitive method to detect for minute amounts of contaminating undifferentiated iPS cells

2022 Clarivate Highly Cited Researchers include six from KyotoU

Immunosuppressive regimens after a heart transplant can hamper good therapeutic progressions in fibrosis

A novel method for generating naive human iPS cells with significantly higher differentiation potency

A novel method for generating naive human iPS cells with significantly higher differentiation potency

Successful generation of human iPS cell-derived mesenchymal cells capable of producing alveolar organoids

Successful generation of human iPS cell-derived mesenchymal cells capable of producing alveolar organoids

An important host factor in SARS-CoV-2 infection, identified using iPS cell and organoid technology

An important host factor in SARS-CoV-2 infection, identified using iPS cell and organoid technology

Human ‘blastoids’ offer medical hope but also deep ethical challenges

Human ‘blastoids’ offer medical hope but also deep ethical challenges

A study using an organ-on-a-chip reveals a mechanism of SARS-CoV-2 invasion into blood vessels ~Disruption of vascular endothelial barrier in respiratory organs by decreasing Claudin-5 expression~

A study using an organ-on-a-chip reveals a mechanism of SARS-CoV-2 invasion into blood vessels ~Disruption of vascular endothelial barrier in respiratory organs by decreasing Claudin-5 expression~

A new method for inducing mesenchymal stem cells from iPS cells without using animal-derived components

A new method for inducing mesenchymal stem cells from iPS cells without using animal-derived components

New Method for Cell Sorting Utilizing microRNA Switch and Magnetic Microbeads

New Method for Cell Sorting Utilizing microRNA Switch and Magnetic Microbeads

COVID-19 Research Using Bronchial Organoids and Drug Discovery Applications

COVID-19 Research Using Bronchial Organoids and Drug Discovery Applications